{"id":1156,"date":"2016-08-27T13:15:54","date_gmt":"2016-08-27T17:15:54","guid":{"rendered":"https:\/\/acadiantest.cocompass.com\/?page_id=1156"},"modified":"2018-06-29T16:00:05","modified_gmt":"2018-06-29T20:00:05","slug":"basic-explanation-genetic-dna-applies-genealogy","status":"publish","type":"page","link":"https:\/\/acadiantest.cocompass.com\/fr\/genealogy\/genealogy-and-dna\/basic-explanation-genetic-dna-applies-genealogy\/","title":{"rendered":"A Basic Explanation of Genetic DNA as it Applies to Genealogy"},"content":{"rendered":"<p align=\"CENTER\">\n<table border=\"2\" width=\"90%\" align=\"center\">\n<tbody>\n<tr>\n<td bgcolor=\"#CCFFFF\">\n<h4>A Basic Explanation of Genetic DNA as it Applies to Genealogy<\/h4>\n<\/td>\n<\/tr>\n<tr>\n<td>December 3, 2010:<\/p>\n<p>In my continued effort to understand the principles of genetic DNA as it applies to genealogy, I asked <a href=\"mailto:szsears@yahoo.ca\">Suzanne Sears<\/a> (Co-Administrator of the Cyr Surname DNA Group Project, which I Administer), to provide me a _basic_ explanation of the process, as it pertains to Pierre Sire (my first ancestor) and my own DNA testing.<\/p>\n<p>In part, my message to Suzanne stated: &#8220;Suzanne, I still have difficulty getting my head around how Pierre Sire can be traced, when we don&#8217;t (obviously) have HIS DNA&#8230; and never will. Can you give me a _simple_ [actually, _very simple_] \ud83d\ude42 explanation!&#8221;<\/p>\n<p>Here is Suzanne&#8217;s reply:<\/p>\n<p>We DO have Pierre&#8217;s DNA&#8230;&#8230;&#8230;&#8230;.You and Peter (another tested member of the Cyr Surname DNA Group)&#8230;&#8230;&#8230;.an exact copy&#8230;&#8230;&#8230;.that&#8217;s why you two are nearly perfect copies of each other&#8230;&#8230;. and you both descend from Pierre.<\/p>\n<p>It works like this&#8230;&#8230;&#8230;&#8230;.<\/p>\n<p>Lets assume Pierre is one of 5 original men on the planet&#8230;&#8230;&#8230;..for now.<\/p>\n<p>DNA is two spindles of thread&#8230;&#8230;&#8230;..<\/p>\n<p>One male<br \/>\nOne female<\/p>\n<p>Those two spindles are the blueprints for making a human being.<\/p>\n<p>The two spindles twirl around each other&#8230;&#8230;&#8230;&#8230;<\/p>\n<p>But if you break them apart:<\/p>\n<p>you will get<\/p>\n<p>one female spindle<br \/>\none male spindle<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>So when Pierre took a wife&#8230;&#8230;&#8230;..<\/p>\n<p>to make a new human being&#8230;&#8230;&#8230;<\/p>\n<p>His DNA spindle broke apart&#8230;&#8230;&#8230;&#8230;into a male and a female portion&#8230;&#8230;..<\/p>\n<p>The female portion was scrapped&#8230;&#8230;&#8230;only the male portion would go forward to be used for the baby<\/p>\n<p>His wife: same thing: her DNA broke apart&#8230;&#8230;&#8230;&#8230;.<\/p>\n<p>her female DNA<br \/>\nher male DNA&#8230;&#8230;&#8230;<\/p>\n<p>But now the male part is scrapped and only the female part goes ahead&#8230;&#8230;..<\/p>\n<p>&#8212;&#8212;&#8212;-<\/p>\n<p>So we take the male thread from Pierre<br \/>\nthe female part from Marie Bourgeois<\/p>\n<p>and bingo: you have Jean Baptiste&#8230;&#8230;&#8230;..and Jean Francois, and Guillaume<\/p>\n<p>Each one of these men carries that first thread from Pierre&#8230;&#8230;&#8230;&#8230;&#8230;in a near perfect copy&#8230;&#8230;.the odd mutation.<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>And every single male from then onwards:<\/p>\n<p>always is using that same first thread of Pierre<\/p>\n<p>So you today: are a mix of Pierres first thread and whomever your mother was&#8230;&#8230;&#8230;<\/p>\n<p>But Pierres original thread is in you&#8230;&#8230;&#8230;&#8230;<\/p>\n<p>and for every male for all time: down the Pierre Sirre lineage:<br \/>\nis a copy of Pierre&#8230;&#8230;&#8230;.<\/p>\n<p>It never never never changes&#8230;&#8230;..not the male DNA&#8230;&#8230;&#8230;&#8230;down the male side&#8230;&#8230;&#8230;&#8230;.<br \/>\nsame original thread used to make every single male for all of history<br \/>\n&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>The question we dont know is: who did Pierre get his thread from&#8230;&#8230;&#8230;who was his father&#8230;&#8230;&#8230;..<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>12 markers is a good idea of the basic white cotten thread<br \/>\n(using a picture)<\/p>\n<p>that was the starting point anciently&#8230;&#8230;&#8230;&#8230;<\/p>\n<p>So using your imagination now<\/p>\n<p>think back 1,000 years&#8230;&#8230;&#8230;..and there is a tribe somewhere in Germany of 10 men&#8230;&#8230;<br \/>\none of those men was carrying that thread&#8230;&#8230;&#8230;.<\/p>\n<p>and spread it forward through sons to get to Pierre&#8230;&#8230;&#8230;&#8230;&#8230;and now you and Peter<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>Pierre lives in you&#8230;&#8230;&#8230;&#8230;..if he was here: even 400years later: your male DNA would be an identical match within just a small variation&#8230;&#8230;<\/p>\n<p>No one else on this planet would match Pierre Sirre better than you and Peter&#8230;&#8230;&#8230;.<\/p>\n<p>Time makes little to no difference<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>Example: they found a cave in Germany with about 3,000 old skeletons: obviously from some kind of war<\/p>\n<p>So on whim: they said: lets test people nearby&#8230;&#8230;&#8230;&#8230;..within 30k&#8230;&#8230;&#8230;.to see who was here back then and who is here now<\/p>\n<p>And they found genetic matches!!!!<\/p>\n<p>People genetically related to these dead guys from 3,000 years ago: all still living in the same damn place.<\/p>\n<p>Thats why DNA is valuable for geography: people really dont move all that much&#8230;&#8230;&#8230;.despite modern times.<\/p>\n<p>Like you expect to find polar bears in the Arctic: but if you find one in the North West Territories: you arent too surprised: but it might be just a few.<\/p>\n<p>Well people are pretty much like that too&#8230;&#8230;&#8230;&#8230;&#8230;a few move: most dont shift far from their ancestral homes.<\/p>\n<p>&#8212;&#8212;-<\/p>\n<p>So using Pierres DNA we can without a doubt find where he came from:<br \/>\nand right now the best information is Flanders<\/p>\n<p>possibly over to Belgium and Holland&#8230;&#8230;&#8230;<\/p>\n<p>This is his ancestral home base&#8230;&#8230;&#8230;..<\/p>\n<p>doesnt mean he lived there in 1644&#8230;&#8230;&#8230;only that most of his kin folk did.<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>Hope this helps a bit&#8230;&#8230;&#8230;<\/p>\n<p>There are no unique human beings: each of us is a copy of someone who lived before right back to 250,000 years ago.<\/p>\n<p>Of the native women in Canada: they all come from just 5 original women: 250,000 years ago.<\/p>\n<p>Each one alive today is a copy of one that lived then.<\/p>\n<p align=\"left\">Here&#8217;s an easier way to understand what I wrote in the previous email<\/p>\n<p>Imagine:<\/p>\n<p>A white thread in your left hand: a Male thread<br \/>\nA black thread in your right hand: a Female thread<\/p>\n<p>Now twist and twirl them together=a new human being<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>Lets argue it&#8217;s a son&#8230;&#8230;&#8230;&#8230;.<\/p>\n<p>Now this son gets married and has a baby<\/p>\n<p>His threads unravel&#8230;&#8230;&#8230;..and goes back to being separate threads<\/p>\n<p>One white male thread<br \/>\nOne black female thread<\/p>\n<p>Just like it was when his parents got together and shared their DNA to make him&#8230;&#8230;<\/p>\n<p>His wifes DNA will do the same thing&#8230;&#8230;&#8230;<\/p>\n<p>she too has her DNA broken down into 2 threads&#8230;&#8230;..<br \/>\none male from her Dad<br \/>\none female from her Mom<\/p>\n<p>So now we are going to make a new human&#8230;&#8230;&#8230;<\/p>\n<p>We will take the male thread from this original son<br \/>\nWe will take the female thread from the new wife<\/p>\n<p>(the rest is scrapped: the male dumps his female thread<br \/>\nthe female dumps her male thread)<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>So now we have:<\/p>\n<p>a white thread from the male son<br \/>\na black thread from the female new wife<\/p>\n<p>and they twist back up to make a new person&#8230;&#8230;&#8230;&#8230;<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>the key point to remember though is:<\/p>\n<p>That white male thread is the same darn white male thread this new father to be<br \/>\ngot to begin with<\/p>\n<p>He never got new white threads&#8230;&#8230;..<br \/>\nHis son will never get new white threads&#8230;&#8230;.<\/p>\n<p>for the next 100,000 years:<\/p>\n<p>all the males will reuse that same white male thread:<br \/>\nfor every new male born<\/p>\n<p>thats why your white male thread is a copy of Pierre&#8230;&#8230;&#8230;..<br \/>\nbecause its the only white thread he had to pass on&#8230;&#8230;.<\/p>\n<p>and he got it from his Dad<br \/>\nand he got it from his Grandfather<\/p>\n<p>and all your sons will have that same white thread&#8230;<\/p>\n<p>250,000 years from now:<\/p>\n<p>All males that descend from Pierre will still be using that same white thread&#8230;&#8230;.<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>It just keeps unravelling and then tieing back up as each child is born<br \/>\njust the female thread changes in the equation<br \/>\nsince each new generation has a new Mom&#8230;&#8230;&#8230;<\/p>\n<p>And thats why we only use Male DNA to do the tracking with&#8230;&#8230;&#8230;&#8230;.because its the same white thread since the beginning of time&#8230;&#8230;..with just a very few breakages or mutations along the way<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>Its only the female DNA that creates variation&#8230;&#8230;.mtDNA&#8230;&#8230;&#8230;.<\/p>\n<p>but we will never know Pierres female DNA thread&#8230;&#8230;&#8230;because he never had any sisters that we know of&#8230;&#8230;&#8230;.and he doesnt pass forward female DNA&#8230;&#8230;..only his own male DNA&#8230;..<\/p>\n<p>The male DNA never never changes&#8230;&#8230;&#8230;&#8230;.<\/p>\n<p>It&#8217;s a recipe&#8230;&#8230;..that never changes&#8230;&#8230;&#8230;&#8230;<\/p>\n<p>&#8212;&#8212;&#8212;-<\/p>\n<p>So when they do DNA testing:<br \/>\nthats exactly what they do<\/p>\n<p>they break the male and female threads apart:<\/p>\n<p>and give you the outline of the male thread&#8230;&#8230;<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;-<\/p>\n<p>The numbers indicate how many&#8230;&#8230;..<\/p>\n<p>so for example:<\/p>\n<p>At maker 390=23<\/p>\n<p>It means: in that small space called 390&#8230;&#8230;&#8230;..there are 23 repeats of a chemical&#8230;&#8230;..<\/p>\n<p>In my DNA at 390= I have 24 repeats of that chemical&#8230;&#8230;&#8230;<\/p>\n<p>Thats how we know we arent bloodline related&#8230;&#8230;&#8230;&#8230;<\/p>\n<p>Because Pierres thread carried 23 repeats<br \/>\nand its nearly impossible for that to randomly become 24 repeats in only 400 years.<\/p>\n<p>The pattern of the thread repeats itself so nearly perfectly each time.<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>so on a tribal level:<\/p>\n<p>only persons with 23 repeats at 390 share the same tribal background: the Frankish Germans<\/p>\n<p>and I share a tribal background with those humans who had 24: &#8230;&#8230;&#8230;the Celts<\/p>\n<p>this is how they know that Germans and Celts were not the same race of people&#8230;&#8230;.<\/p>\n<p>&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;&#8212;<\/p>\n<p>When you review basic 12 marker tests for the numbers:<\/p>\n<p>it is telling you how many repeats there are at each step along the way<\/p>\n<p>13 23 14 11<\/p>\n<p>Means&#8230;<br \/>\nstep one: 13 repeats<br \/>\nstep two: 23 repeats<br \/>\nstep three: 14 repeats<br \/>\nstep four: 11 repeats<\/p>\n<p>Now they can tell you: that people with this exact pattern of repeated numbers:<br \/>\nlived in a certain geography at a certain time in history&#8230;&#8230;&#8230;.<\/p>\n<p>they can track them backwards in time to the biggest concentrations of these patterns<br \/>\nwhere they are today<br \/>\nwhere they said they came from<br \/>\nwhere they were before<\/p>\n<p>&#8212;&#8212;&#8212;<\/p>\n<p>Mine is: 13 24 14 10&#8230;&#8230;&#8230;and they can also tell you where that pattern was back in time&#8230;&#8230;&#8230;<\/p>\n<p>So while your people were somewhere in Frankish German territory<br \/>\nmine were busy in Celtic regions: specifically Ireland<\/p>\n<p>&#8212;&#8212;&#8212;-<\/p>\n<p>These are called Clusters&#8230;&#8230;&#8230;and certain patterns of numbers cluster in certain geographies<\/p>\n<p>Just like Penguins: who have their own DNA are not found in the Sahara in general&#8230;&#8230;&#8230;<br \/>\nbut cluster in the Antarctic&#8230;&#8230;&#8230;<\/p>\n<p>And Pierres pattern clusters around Holland&#8230;&#8230;some to the left and some to the south and some to the north&#8230;&#8230;&#8230;.<\/p>\n<p>In particular he shares some unique marker repeat sequences<br \/>\nthat are usually found in Flanders only&#8230;&#8230;&#8230;..<\/p>\n<p>yDNA and mtDNA are NOT the same thing:<br \/>\nthey aren&#8217;t equal but rather opposite forms of each other&#8230;&#8230;<\/p>\n<p align=\"left\">yDNA is the &#8220;thread&#8221; that passes strictly from male to male for all time&#8230;&#8230;..<\/p>\n<p>Females DON&#8217;T have it&#8230;&#8230;..<br \/>\nmtDNA: comes strictly from FEMALES; but BOTH males and females get it passed to them from their mother&#8230;..<br \/>\nmtDNA: is the very smallest chromosome:<\/p>\n<p>Humans are made up of 23 pairs of chromosome: = 46 total<br \/>\nOne complete set from each parent:<\/p>\n<p>They are numbered one through 23:<\/p>\n<p>from smallest size to largest size<\/p>\n<p>The number 23 Chromosome is the one which determines our sex one; whether we are male or female.<br \/>\nSo except for chromosome number 23, all humans are fundamentally identical in makeup<br \/>\nOn chromosome number 23, males differ:&#8230;&#8230;..<br \/>\nFemales get two big copies of what we call X&#8230;&#8230;.they are thus XX at number 23<br \/>\nMales get one X and one Y&#8230;&#8230;&#8230;<br \/>\nIt&#8217;s that Y that is used to do the genetic testing called yDNA testing<br \/>\nand there is NO female contribution in that chromosome. None. 100% of it came only from the male ancestors<br \/>\nmtDNA is tested from chromosome number one:<br \/>\nThe Mom is the supplier, but she supplies it to BOTH her male and female offspring&#8230;&#8230;.<br \/>\nYour mtDNA is from Mom; but both brothers and sisters will have the same one too<br \/>\nSo if we took Pierre for an example:<br \/>\nHe ONLY carried the YDNA from his father: and it is what all the Cyr men carry forward<br \/>\nBUT<br \/>\nHe carried the mtDNA of his Mom&#8230;&#8230;.and all previous females down his tree&#8230;..<br \/>\nBUT he could NOT pass it forward&#8230;&#8230;so it died with him<br \/>\nOnly if he had had a sister, would the mtDNA go forward<br \/>\notherwise: it stopped at his generation in his particular tree<br \/>\nThus mtDNA in sons Jean Baptiste, Jean Pierre and Guillaume came from Marie Bourgeois:<br \/>\nbut since they were all males with no sisters<br \/>\nHER DNA died for the Cyr lineage anyway<br \/>\n(I can&#8217;t recall if she had a daughter by subsequent marriage)<br \/>\n-if she did, it passed forward that way.<br \/>\nSo mtDNA tells us something about mothers<br \/>\nall your brothers and sisters would have the same mtDNA<br \/>\nbut<\/p>\n<p>it tells you nothing about the male lineage<br \/>\nmtDNA is stronger and lasts longer than yDNA<br \/>\nso in skeletons, sometimes its all that one can test<br \/>\nMost of the ancestors in North America people want to know about are original males,<br \/>\nmainly because they represented the overwhelming number of unknowns<br \/>\nFurther, one would have to know the vastly more complex maternal family trees to use mtDNA to track<br \/>\nas women names changed every time they got married or in France inherited new estates<br \/>\nIts massively complex to track these multiple last names<br \/>\nthrough several marriages and inheritances<br \/>\nand much more simple to track male names, as they rarely changed<br \/>\n<a href=\"mailto:szsears@yahoo.ca\">Suzanne Sears<\/a><\/p>\n<p align=\"left\">[Note from Yvon: Suzanne is the Co-Administrator of my Cyr Family DNA Group Project]<\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p align=\"center\"><a href=\"http:\/\/www.familytreedna.com\/group-join.aspx?Group=Cyr&amp;code=K65428\" target=\"_blank\" rel=\"noopener\">Click here to have your own Cyr DNA tested<\/a><\/p>","protected":false},"excerpt":{"rendered":"<p>A Basic Explanation of Genetic DNA as it Applies to Genealogy December 3, 2010: In my continued effort to understand the principles of genetic DNA as it applies to genealogy, I asked Suzanne Sears (Co-Administrator of the Cyr Surname DNA Group Project, which I Administer), to provide me a _basic_ explanation of the process, as [&hellip;]<\/p>","protected":false},"author":2,"featured_media":0,"parent":1150,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_crdt_document":"","_themeisle_gutenberg_block_has_review":false,"iawp_total_views":0,"footnotes":""},"class_list":["post-1156","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.6 - 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